Case Study

Uganda – TB screening among people living with HIV using Delft Light and CAD4TB

Delft Light in Uganda

People living with HIV are at increased risk of TB and often require intensified screening. TB screening was implemented at selected health facilities in Uganda to improve case detection among this priority population.

Facility-based screening for PLHIV

Five health facilities conducted TB screening among people living with HIV.

Using ultra-PDX with CAD4TB

Screening was performed using digital chest X-ray supported by CAD4TB.

Identify presumptive TB cases

Individuals with CAD4TB scores above 60 were identified as presumptive TB cases.

Confirmatory testing

Presumptive TB cases were tested using Xpert MTB/RIF, and confirmed cases initiated TB treatment.

Result

From July 2020 to November 2021,

4 ,463 individuals
were screened with X-rays
69 1 people
had abnormal CXR
36 8 people
tested using Xpert MTB/RIF
4 8 people
confirmed with TB
  • Among those screened, 22.7% were PLHIV, 165 (16.3%) had abnormal CXR, and 20 PLHIV (21.5%) were confirmed with TB.
Delft Light in Uganda
Conclusion
  • TB screening with CXR improved TB case detection with higher yield among PLHIV and contacts compared to other groups.
  • Using digital X-rays and CAD for routine screening of TB among PLHIV in care should be prioritised for early TB diagnosis, treatment initiation and improved outcomes.

REFERENCE: B. Aldo et al. (2022, November 8-11. Intensified TB case-finding using digital X-ray and CAD4TB among people living with HIV receiving care at health facilities in Uganda. The Union World Conference on Lung Health 2022.