Case Study

Mozambique – Prevalence of asymptomatic TB with CAD4TB

CAD4TB in Mozambique

The study investigates the prevalence of subclinical TB based on three case definitions and suggests implications for TB control in Mozambique.

Nationwide data analysis

A cross-sectional secondary analysis was conducted using data from a national TB prevalence survey.

Adult population screening

Adults aged 15 years and above were screened for TB symptoms and underwent chest X-ray with CAD4TB.

AI-supported triage

Screening combined symptom assessment and CAD4TB analysis to identify presumptive TB cases.

Sputum sample collection

Individuals who screened positive were asked to submit sputum samples for further evaluation.

Result

Out of 70,114 individuals, 32,445 (74.9%) participated in the survey, 10,831 were eligible for sputum collection, and 121 had MTB detected. 89 were classified as survey TB cases.

Among 89 survey TB cases,

59 .5%
had no persistent cough
51 .5%
had no cough
43 .8%
had no TB suggestive symptoms
  • TB was more frequent among male, individuals between 25 and 44 years old in urban settings.
  • More than 80% of CXR show some abnormalities.
CAD4TB in Mozambique
Conclusion
  • The study found a high prevalence of subclinical pulmonary TB in Mozambique and high TB burden countries.
  • The results suggest that TB may need to review the screening guidelines to identify subclinical cases effectively.

REFERENCE: Manhica, I. et al (2024, November 12-16). Prevalence of subclinical pulmonary TB in Mozambique: Implications for TB Screening [Presentation]. The Union World Conference on Lung Health, Bali, Indonesia.