Published on 13 February 2026, Last update on 23 February 2026
3 minutes
Over the years, different stakeholders in Malawi have published about utilizing the OneStopTB clinics and the CAD4TB software. Their scientific efforts showed that digital CXR using CAD4TB with universal HIV screening significantly increased timelines and completeness of HIV and TB diagnosis.
The CASTLE study in Malawi used CAD4TB to enhance TB diagnosis in adults with HIV through computer-aided chest X-rays and urine LAM tests. This cluster randomized trial demonstrated improved diagnostic accuracy for TB in hospitalized patients. Read the full study here.